Minoxidil topical solution was derived from oral minoxidil (Loniten).
Minoxidil is a vasodilator that opens-up the blood vessels thereby increasing capillary blood flow. Studies suggest that it has a direct stimulating effect on the hair follicle cells, but exerts no antiandrogen (anti–male hormone) influences.
Side effects from topical minoxidil are usually of a non-serious allergic nature; itchy/flaking scalp or a scalp rash. Very rarely, some sensitive individuals have experienced cardiac-like chest pain, breathlessness, or abdominal pain. Adverse reactions resolve once the drug is withdrawn.
Minoxidil remains the only topical solution approved by the US FDA to stimulate follicle hair growth. The original indication for men stated: “for male pattern baldness of the vertex” (crown). It is now known the drug works equally well on a balding frontal area, or for any hair loss condition on the body where the hair follicles are still functional.
Under various brand names, minoxidil is available ‘over the counter’ in 5% and 2% strengths. However these commercial preparations are known to be poorly absorbed, and the propylene glycol additive is the predominant cause of the itching/flaking scalp side effects.
By removing the propylene glycol, and adding penetration enhancers/androgen blockers, ‘second generation’ formulas of minoxidil are now available, which are far more effective, user friendly, and with minimal adverse reactions. Minoxidil solutions can now be formulated in 3-10% strengths, and be targeted to specific hair loss conditions.
Most significantly, the majority of women experiencing androgenetic alopecia will no longer have to take the oral ‘anti-androgen’ (anti-male hormone) medication to help suppress the problem. Males need only take Provillus as a combination therapy for about 12 months.
To learn more about Minoxidil in combination with Provillus Click Here.
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